Elucidating the exact pharmacological mechanism of action (MOA) of naturally happening compounds is usually tough. Though Tarselli et al. (60) developed the primary de novo artificial pathway to conolidine and showcased that this naturally happening compound efficiently suppresses responses to both chemically induced and inflammation-derived pain,

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Scientists have not long ago determined and succeeded in synthesizing conolidine, a all-natural compound that demonstrates assure as a potent analgesic agent with a more favorable safety profile. Even though the exact mechanism of action remains elusive, it can be now postulated that conolidine could possibly have many biologic targets. Presently,

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